Whole genome methylation profiliing between the IMU and KRT subtypes of HPV-associated head and neck cell carcinoma (HNSCC)

We compared the whole-genome methylation profiles between IMU and KRT samples in a 36 HNSCC cohort and identified 270,326 differentially methylated regions (DMRs; FDR < 0.05 and absolute methylation difference >= 20%) between IMU and KRT HPV(+) subtypes. WGBS was performed on 36 HNSCC samples (the same cohort in GSE74956), and the differential methylated regions were identified between IMU (n=8) and KRT (n=10) HPV(+) HNSCC samples. The file IDmapping.csv, available at the foot of this record, provides the titles of the corresponding samples between GSE74956 and this series.