Ten SNPs with lowest P-values for overall association with PFS.

Abbreviations: HR, Hazard ratio; Chr, chromosome; CI, confidence interval; n.a., marker is not localized within a gene. ARHGEF4: Rho guanine nucleotide exchange factor 4.
* R2: imputation accuracy. A0: reference allele according to hapmap2, A1: alternate allele.
# HR assuming an additive effect depending on dosage of the alternate alleles, obtained with multivariate Cox-proportionale hazards model, including age, gender, treatment arm, and the interaction treatment arm* marker as covariates.
Ten SNPs with lowest P-values for overall association with PFS.