Alpha-7 nicotinic acetylcholine receptor bound to epibatidine in a desensitized state

Alpha-7 nicotinic acetylcholine receptor bound to epibatidine in a desensitized state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Noviello, C.M, Hibbs, R.E, Gharpure, A, Mukhtasimova, N, Cabuco, R, Baxter, L, Borek, D, Sine, S. Deposit date: 2020-11-09 Release date: 2021-03-17 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor. Cell, 184, 2021

本数据集为处于脱敏状态的α7烟碱型乙酰胆碱受体（Alpha-7 nicotinic acetylcholine receptor）与依巴替丁（epibatidine）的结合体。描述符：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、钙离子（CALCIUM ION）等。作者：Noviello, C.M、Hibbs, R.E、Gharpure, A、Mukhtasimova, N、Cabuco, R、Baxter, L、Borek, D、Sine, S。存档日期：2020-11-09；发布日期：2021-03-17；最后修改日期：2025-06-04。实验方法：电子显微镜（ELECTRON MICROSCOPY），分辨率3.6埃（Å）。引用文献：《α7烟碱型乙酰胆碱受体的结构与门控机制》（Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor），刊载于《细胞》（Cell）第184卷，2021年。