Stress granule assembly impairs macrophage efferocytosis [RNA-seq]

Stress granules (SGs) assembly in response to various stress, has been demonstrated in the regulation of anti-viral immune response and tumor progression. However, lack of evidence to illustrate the relation between SGs formation and allergic diseases. Applying RNA-seq in primary macrophages from G3bp1f/f and G3bp1mac-/- mice, differential expressed genes were defined. Overall design: RNA-seq is undertaken to investigatethe differential expressed genes in primary macrophages between G3bp1f/f and G3bp1mac-/- mice.