five

PACIFIC dataset_main figures

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Recherche Data Gouv France2024-01-01 更新2026-04-09 收录
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https://entrepot.recherche.data.gouv.fr/citation?persistentId=doi:10.57745/AQUNJA
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The aim of the PACIFIC study is to compare 46 AIEC bacteria isolated from Crohn's patients in France and Hong Kong between 2017 and 2022. Their adhesion and invasion to intestinal epithelial cells phenotype was tested. Colonisation of the gut of a mouse model mimicking Crohn's disease by 4 strains isolated in France and 4 strains isolated in Hong Kong was compared. The sequencing of 46 strains was carried out and the raw data used for the genomic analyses is compiled in a file. The isolated strains were also tested for antibiotic resistance and sensitivity to a cocktail of phages.
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