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ChIP-seq and RNA-seq study of human FXR in primary human hepatocytes and microarray analysis of GW4064 versus vehicle treated wild type mouse livers

NIAID Data Ecosystem2026-05-26 收录

核受体FXR转录调控

肝脏代谢调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA246226 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2014-05-05

转录因子结合位点分析

肝脏代谢调控

To clarify mouse PPARA autoinduction and hepatocyte proliferation signaling pathways, genome-wide distribution of PPARA in the liver of PPARA agonist-treated mice compared to Vehicle was analyzed. ChI

NIAID Data Ecosystem90

Effect of hepatocyte-restricted deletion of PPARalpha on liver gene expression in response to fasting in mice from both sexes

肝脏代谢调控

PPARalpha基因功能

Wild-type (LWT) and mice with hepatocyte restricted deletion of PPARalpha (LKO) mice were fasted fro 24 hours. Gene expression was analyzed in the liver of Wild-type (LWT) mice and in the liver of mic

NIAID Data Ecosystem40

Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets

仔猪营养管理

肝脏代谢调控

The objective of this study was to reveal the effects of early life lactoferrin intervention on the liver metabolism in the suckling piglets. Sixty newborn piglets with an average initial body weight

NIAID Data Ecosystem40

Impacto do tempo de restrição alimentar e exercício físico resistido no metabolismo hepático de camundongos alimentados com dieta hiperlipídica

肝脏代谢调控

营养与运动

Dados referentes as análises fisiológicas, histológicas e moleculares dos animais alimentados com dieta hiperlipídica e submetidos a associação ou não das intervenções do tempo de restrição alimentar

DataCite Commons2025-02-10 更新50

Liver transcriptome data of Esr1 knockout male rats reveals altered expression of genes involved in carbohydrate and lipid metabolism.

肝脏代谢调控

基因表达分析

Estrogens are traditionally considered to be female sex steroid hormones and most of the studies examining estrogen regulation of metabolic function in the liver have been conducted in females. Howeve

NIAID Data Ecosystem40

ChIP-seq and RNA-seq study of human FXR in primary human hepatocytes and microarray analysis of GW4064 versus vehicle treated wild type mouse livers

资源简介：

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