Global gene expression profiling of M. tuberculosis H37Rv and the isogenic regX3-inactivated mutant (DregX3) grown in phosphate enriched or phosphate-limited medium

In order to understand the repertoire of genes regulated by RegX3, we performed microarray analysis of gene expression in M. tuberculosis (WT) or DregX3 grown in phosphate-enriched or phosphate limited medium. The differentially regulated genes provide insight into the role of RegX3 in gene regulation in Mtb. Gene expression profiling was performed in replicates for both the wild type and the isogenic DregX3 grown in phosphate enriched or phosphate limited conditions.