Proteomic changes associated with sperm fertilizing ability in meat type roosters

The molecular basis of male infertility is still not well understood. Furthermore, in vitro sperm quality tests are poorly correlated to in vivo fertility. In order to better understand sperm biology and determine potential fertility biomarkers, we used a quantitative bottom-up proteomic approach to identify proteins relative to sperm fertilizing ability in meat roosters, suffering from fertility reduction due to genetic selection side effects.