Trait Demographics, Test-Retest Reliability, Phenotypic/Genetic Correlations, and Twin Correlations (shown with 95% Confidence Intervals).
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aRC was derived from principal components analysis (PCA) of the Sentence Comprehension, N-term, and Latin Square tasks and accounted for 63.9% of variance. Reasoning, accounting for 70.2% of the variance in PCA, was derived from the Matrix Reasoning and Arithmetic subtests from the WAIS-III [40] and MAB [39] respectively (note that Arithmetic is contributing to both IQ and Reasoning). Working Memory, accounting for 79.1% variance in PCA, was derived from Digit Span Backwards and Letter Number Sequencing (WAIS-III [40]). IQ was derived from scaled scores from three verbal (Information, Arithmetic, Vocabulary) and two performance subtests (Spatial, Object Assembly) from the MAB [39].b For genome-wide association, a larger sample (1999) was used.c Based on 20 pairs retested for RC and Working Memory (mean interval = 3.3±1.6 months) and an independent set of 50 pairs retested for IQ (mean interval = 3.4±1.0 months) [85]. Test-retest for Reasoning could not be computed due to non-overlap of retest samples for the contributing variables. Note that reliability for Latin Square increased to 0.60 if three individuals showing substantial improvement were dropped.d Genetic correlations were derived from Cholesky decomposition that allowed for additive genetic, common environmental, and unique environmental influences.e MZ = monozygotic, DZ = dizygotic. Note that twins were paired with a non-twin sibling where possible to create additional pseudo-DZ pairs. For all variables, correlations between same-sex co-twins could be collapsed over sex for MZ and DZ pairs (i.e. MZ male and female pairs, DZ male and female pairs, Δχ21 ranged 0.0–2.5) indicating that the magnitude of genetic and environmental influences did not differ significantly between males and females. Further, indicating that sources of influence do not differ significantly between males and females, the opposite-sex correlations could be set equal to the same-sex DZ correlations for all variables (Δχ21 ranged 0.6–3.3), with the exception of IQ (Δχ21 = 4.2). This suggests that for IQ there may not be complete overlap in genetic sources of influence for males and females.Trait Demographics, Test-Retest Reliability, Phenotypic/Genetic Correlations, and Twin Correlations (shown with 95% Confidence Intervals).
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2015-12-03



