化合物毒性数据库

收录了化合物的毒性数据，包括物质的各种毒性实验数据、美国研究状况和化合物毒性标准、各国职业场所化合物毒性暴露限度、毒性作用、相关参考文献等信息。 毒性数据包括了毒性实验类型(如急性毒性、致突变性、生殖毒性等)、测试类型（如LD50、LC50等）、测试物种(如大鼠、小鼠、兔等)、接触途径（如口服、腹腔注射、静脉注射）以及使用剂量。用户可以根据这些实验数据对化合物进行筛选。 毒性作用则包括了各种毒理作用，如肝毒性、神经毒性、耳毒性等。This dataset collects comprehensive toxicity-related data for chemical compounds, including various toxicological experimental data, the research status of compound toxicity in the United States, compound toxicity standards, occupational exposure limits of compounds in national workplaces, toxic effects, and relevant references. The toxicity data covers categories of toxicological experiments (e.g., acute toxicity, mutagenicity, reproductive toxicity, etc.), test endpoints (e.g., LD50, LC50, etc.), test species (e.g., rats, mice, rabbits, etc.), exposure routes (e.g., oral administration, intraperitoneal injection, intravenous injection), and administered doses. Users can screen chemical compounds based on these experimental data. The toxic effects include various toxicological actions, such as hepatotoxicity, neurotoxicity, ototoxicity, etc.

搜集汇总

背景与挑战

背景概述

该数据库收录了15.3万条化合物毒性数据，涵盖急性毒性、致突变性等多种实验类型，包括LD50、LC50等测试指标以及大鼠、小鼠等测试物种。数据涉及毒性作用如肝毒性和神经毒性，并提供了各国职业暴露限度和相关参考文献，支持用户进行化合物筛选分析。