Development of peptidomimetic inhibitors of the ERG transcription factor in prostate cancer (ChIP-seq)

ChEBI2014-07-15 更新2026-07-21 收录

前列腺癌靶向治疗

转录因子抑制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58939 数据链接链接失效反馈

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Development of peptidomimetic inhibitors of the ERG transcription factor in prostate cancer (ChIP-seq)

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2014-07-15

Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer

前列腺癌靶向治疗

DYRK2

Prostate cancer (PCa) is a common male cancer with high incidence and mortality, and hormonal therapy as the major treatment for PCa patients is troubled by the inevitable resistance that makes us ide

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Physachenolide C is a Potent, Selective BET Inhibitor

BET抑制剂

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A pulldown using a biotinylated natural product of interest in the 17β-hydroxywithanolide (17-BHW) class, physachenolide C (PCC), identified the bromodomain and extra-terminal domain (BET) family of p

Figshare2022-12-28 更新80

Pathway based integrative analysis reveals a key role for the hexosamine biosynthetic pathway in prostate cancer progression with therapeutic implications. Homo sapiens

癌细胞代谢

前列腺癌靶向治疗

To better understand the biochemical changes associated with castrate resistant prostate cancer (CRPC), we developed a pathway-based integrated analytical method to examine prostate cancer (PCa) gene

NIAID Data Ecosystem40

Integrated omics profiling reveals FOXA1 and Ku70/Ku80 as the direct target of ivermectin for prostate carcinogenic inhibition

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药物机制研究

Here, we show that ivermectin suppress prostate cancer progression by inhibiting AR signaling pathway and attenuate cellular DNA damage repair capacity. We applied an integrated omics profiling includ

NIAID Data Ecosystem80

New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

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药物化学与药效学

In our effort to find small-molecule treatments of advanced prostate cancers (PCs), a novel series of indolyl and indolinyl propanamides (series II and III) were discovered as selective androgen recep

NIAID Data Ecosystem60

Development of peptidomimetic inhibitors of the ERG transcription factor in prostate cancer (ChIP-seq)

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