IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
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IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN Descriptor: 3-HYDROXY-2H-CHROMEN-2-ONE, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H. Deposit date: 2013-02-15 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules. J.Med.Chem., 56, 2013
人D-氨基酸氧化酶的体外与体内抑制作用：大脑中D-丝氨酸浓度的调控
描述符：3-羟基-2H-色烯-2-酮、D-氨基酸氧化酶（D-amino acid oxidase）、黄素腺嘌呤二核苷酸（Flavin-adenine dinucleotide）……
作者：Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H.
提交日期：2013-02-15
发布日期：2013-05-15
最后修改日期：2023-12-20
研究方法：X射线衍射（2.4 Å）
引用文献：小分子对D-氨基酸氧化酶的结构、动力学及药效学抑制机制. 《药物化学杂志》（J.Med.Chem.）, 56卷, 2013年
创建时间：
2013-02-15
