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PFKFB3 regulates breast cancer tumorigenesis and Fulvestrant sensitivity by affecting ER alpha stability

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP499874
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资源简介:
we find PFKFB3 is a novel regulator of ER alpha and regulates ER alpha stability and activity in the case of estrogen deprivation. Our results further explores an effective approach to improve fulvestrant sensitivity through the early combination with a PFKFB3 inhibitor.
创建时间:
2025-05-01
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