Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in Peripheral T-Cell Lymphoma
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA800774
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资源简介：
Expression of the Vav1-Myo1f fusion oncogene alters T-cell differentiation and induces Gata3 positive Th2 PTCL, NOS with a characteristic macrophage signature clinically linked with poor prognosis. Therapeutic targeting of lymphoma-associated macrophages highlights the role of the tumor microenvironment in supporting lymphoma growth and pinpoints to novel therapeutic approaches for the treatment of high-risk PTCL.
创建时间：
2022-01-26
