x-ray structure of NeoB from Streptomyces fradiae in complex with neamine as an external aldimine

x-ray structure of NeoB from Streptomyces fradiae in complex with neamine as an external aldimine Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside, CHLORIDE ION, Neamine transaminase NeoN Authors: Thoden, J.B, Dow, G.T, Holden, H.M. Deposit date: 2018-02-03 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. Protein Sci., 27, 2018

弗氏链霉菌（Streptomyces fradiae）来源的、与新霉素胺（neamine）形成外部醛亚胺复合物的NeoB蛋白X射线晶体结构。结构描述符：(1R,2R,3S,4R,6S)-4,6-二氨基-2,3-二羟基环己基 2-氨基-2,6-二脱氧-6-[({3-羟基-2-甲基-5-[(膦酰氧基)甲基]吡啶-4-基}甲基)氨基]-α-D-吡喃葡萄糖苷、氯离子（CHLORIDE ION）、新霉素胺转氨酶NeoN（Neamine transaminase NeoN）。作者：Thoden J.B.、Dow G.T.、Holden H.M.。存档日期：2018-02-03；发布日期：2018-02-21；最后修改日期：2023-10-04。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.6 Å。引用文献：《NeoB的三维结构：参与新霉素生物合成的氨基转移酶》，《蛋白质科学》，第27卷，2018年。