Original results and re-analysis of microRNAs in rat brains.

MicroRNAs originally detected in expression data from rat brains by Nielsen et al.[28]. Columns from left to right are the name of the microRNAs, the originally reported results (columns 2-4) and the results of our re-analysis (columns 5-7). Nielsen et al. performed their gene set tests separately for subsets of up- and down-regulated mRNAs yielding two results per gene set. Our re-analysis was performed by use of the combination approach based on either global tests, enrichment tests or rotation tests (‘ROAST’ (R), ‘Romer’ (r)). Significance (sig.) was declared when the FDR-adjusted -value was and not significant (n. s.) otherwise.