Cryo-EM structure of the GD-BatCoV (BtCoV/Ii/GD/2014-422) RBD in complex with human DPP4
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Cryo-EM structure of the GD-BatCoV (BtCoV/Ii/GD/2014-422) RBD in complex with human DPP4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 soluble form,Isoform 1 of Immunoglobulin heavy constant gamma 1, ... Authors: Yuan, H, Xiong, X. Deposit date: 2024-09-20 Release date: 2025-06-18 Last modified: 2025-07-23 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structures and receptor binding activities of merbecovirus spike proteins reveal key signatures for human DPP4 adaptation. Sci Adv, 11, 2025
GD株蝙蝠冠状病毒(GD-BatCoV,BtCoV/Ii/GD/2014-422)受体结合结构域(Receptor Binding Domain, RBD)与人二肽基肽酶4(Dipeptidyl peptidase 4, DPP4)复合物的冷冻电镜结构 描述项:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、可溶性二肽基肽酶4、免疫球蛋白γ1重链恒定区1亚型,…… 作者:Yuan, H、Xiong, X 提交日期:2024年9月20日 发布日期:2025年6月18日 最后修改日期:2025年7月23日 实验方法:冷冻电镜(分辨率3.4 Å) 引用文献:《梅贝科病毒属刺突蛋白的结构与受体结合活性揭示人类DPP4适应性关键特征》,发表于《Science Advances》(Sci Adv)2025年,第11卷



