Heterogeneity analyses by Cochran's Q of unpruned single-trait MR.

Lipid association statistics are from MVP. Estimates are from the IVW method, and the outcome trait was risk for all BC. Exposure: lipid trait used as the exposure; Q: Cochran’s Q statistic; Q_df: degrees of freedom in Cochran’s Q test; Q_P: P-value of Cochran’s Q test. BC, breast cancer; HDL, high-density lipoprotein; IVW, inverse-variance weighted; LDL, low-density lipoprotein; MR, Mendelian randomization; MVP, Million Veteran Program; TC, total cholesterol; TG, triglyceride. (XLSX)