Padanamides A and B, Highly Modified Linear Tetrapeptides Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Padanamides_A_and_B_Highly_Modified_Linear_Tetrapeptides_Produced_in_Culture_by_a_i_Streptomyces_i_sp_Isolated_from_a_Marine_Sediment/2625740
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Two highly modified linear tetrapeptides, padanamides A (1) and B (2), are produced by laboratory cultures of a Streptomyces sp. obtained from a marine sediment. Padanamide B is cytotoxic to Jurkat cells, and a chemical genomics analysis using Saccharomyces cerevisiae deletion mutants suggested that padanamide A inhibits cysteine and methionine biosynthesis or that these amino acids are involved in the yeast’s response to the peptide.
创建时间:
2016-02-23



