Supplementary Material for: Capsule endoscopy-based diagnosis of lung squamous cell carcinoma associated with abdominal pain and metastasis to small intestine：A case report

The gastrointestinal metastases of lung cancer（GMLC）is rare, but is more frequent than expected in patients with longer survival. In particular, the small intestinal metastases often have few or no symptoms, making early diagnosis difficult. We present an extremely rare case of a lung squamous cell carcinoma with abdominal pain metastasis to small intestine. The patient underwent capsule endoscopy, which revealed an irregular mass with hemorrhage in the distal ileum, followed by a ileal resection and anastomosis paralleled by the part of Bladder resection through laparoscopy. The pathological biopsy confirmed that the small intestine mass was consistent with metastatic squamous cell carcinoma. Capsule endoscopy, as a non-invasive test, can quickly and intuitively obtain the etiological diagnosis, and the use of it makes up for the lack of diagnostic methods. Early diagnosis and treatment play a positive role in the prognosis of the GMLC patients.肺癌胃肠道转移（Gastrointestinal Metastases of Lung Cancer, GMLC）虽属罕见，但在生存期较长的患者中，其实际发生率较预期更高。尤为特殊的是，小肠转移往往症状轻微或无明显临床表现，致使早期诊断颇具挑战。本次报告一例极为罕见的肺鳞状细胞癌（Pulmonary Squamous Cell Carcinoma）小肠转移病例，该患者以腹痛为首发症状。患者首先接受胶囊内镜（Capsule Endoscopy）检查，结果显示回肠远端存在伴出血的不规则肿物；随后通过腹腔镜完成回肠切除吻合术（Ileal Resection and Anastomosis），并同期实施部分膀胱切除术（Bladder Resection）。术后病理活检证实，小肠肿物为转移性鳞状细胞癌（Metastatic Squamous Cell Carcinoma）。胶囊内镜作为无创检查手段，可快速直观地明确病因诊断，其应用弥补了现有诊断方法的局限性。早期诊断与治疗对肺癌胃肠道转移患者的预后具有积极意义。