Mycobacterium avium subsp. paratuberculosis MAP4 Genome sequencing

Mycobacterium avium subspecies paratuberculosis (MAP) has been identified in some human patients with Crohn's disease. In order to identify genetic differences between MAP isolates recovered from humans and those associated with bovine Johne’s disease, we characterized the complete genome sequence of strain MAP4 recovered from the breast milk of a Crohn’s disease patient.

牛分枝杆菌亚种结核分枝杆菌（Mycobacterium avium subspecies paratuberculosis，简称MAP）已被确认为某些克罗恩病患者的病原体。为了探究人类分离得到的MAP菌株与与牛结核分枝杆菌病相关菌株之间的遗传差异，我们对从克罗恩病患者母乳中分离得到的菌株MAP4的完整基因组序列进行了表征。