Data from: Expression of taste signal transduction molecules in the caecum of common marmosets

The extraoral presence of taste signal transduction proteins has recently been reported in rodents and humans. Here, we report for the first time the presence of these signal transduction proteins in the caecum of a non-human primate, the common marmoset. Quantitative RT-PCR data on the gene expression of taste signal transduction molecules (gustducin and TRPM5) in common marmosets suggested high expression in the caecum, which was not observed in other non-human primates. Immunohistochemical analysis confirmed the specific presence of gustducin and taste receptors in marmoset caecal cells. These results may relate to the specific feeding behaviour of marmosets, which consume plant exudates, primarily gums.近期有研究报道，啮齿类与人类体内存在口腔外的味觉信号转导蛋白。本研究首次发现，非人类灵长类动物普通狨猴的盲肠中存在这类味觉信号转导蛋白。针对普通狨猴体内味觉信号转导分子（味导素(gustducin)与TRPM5）的实时定量逆转录聚合酶链反应(Quantitative RT-PCR)数据显示，其盲肠中该类分子呈高表达状态，这一现象在其他非人类灵长类动物中并未观测到。免疫组织化学分析进一步证实，狨猴盲肠细胞中特异性存在味导素与味觉受体。上述研究结果或与狨猴的特殊摄食习性相关——狨猴主要以植物渗出物为食，尤以树胶为主。