Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing [WGBS-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE270886
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We investigated the genome-wide DNA methylation dynamics occurring during the C/EBPa-driven B cell to macrophage transdifferentiation. We utilized Whole Genome Bisulfite Sequencing (WGBS-seq) to investigate DNA methylation changes across the genome at a nucleotide level during the process of C/EBPa-driven B cell to macrophage transdifferentiation. The analysis was carried out at four distinct time points (0 hours, 24 hours, 96 hours, and 168 hours).
创建时间：
2025-07-30
