Expression of mRNA in intestinal tissue samples from IBS-D patients and healthy subjects

IBS-D is a disease with multi-factor interaction between environment, central system, gut and gene, and its pathogenesis is relatively complex. In order to find the regulation of mRNA in the pathogenesis of IBS-D, intestinal tissue samples of IBS-D patients and healthy subjects were obtained (5 IBS-D patients,5 healthy subjects), Changes in mRNA expression profiles were detected by high-throughput sequencing. Overall design: Comparative gene expression profiling analysis of miRNA-seq/mRNA-seq data for Intestinal biopsies from IBS-D patients and healthy subjects