Gene expression data of prostate of PND 30 Sprague-Dawley rats (SD:Hsd) dosed prenatally and lactationally with HMB

2-hydroxy-4-methoxybenzophenone (HMB) has been reported to have weak estrogenic activity by in vivo and in vitro studies, making it a chemical with potential reproductive concern. To explore if perinatal HMB exposure altered the gene expression profiling in the rat prostate, we analyzed whole genome and mitochondria-related gene expression profiling on the Prostate ontained from Sprague-Dawley rat offspring exposed prenatally and lactationally to varying dose of HMB.2-羟基-4-甲氧基二苯甲酮（2-hydroxy-4-methoxybenzophenone, HMB）经体内、体外实验研究证实具有弱雌激素活性，属于存在潜在生殖健康隐患的化学物。为探明围产期HMB暴露是否会改变大鼠前列腺的基因表达谱，本研究针对产前及哺乳期暴露于不同剂量HMB的斯普拉-道来（Sprague-Dawley）大鼠子代的前列腺组织，开展了全基因组及线粒体相关基因表达谱分析。