Table S2 from An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs

Table of CpGs used in the analysis and the sources from which they were chosen CpG sites were selected from the recent meta-analysis of Wahl et al. (110). They show that BMI is associated with widespread changes in DNA methylation and genetic associa-tion analyses demonstrate that the alterations in DNA methylation are predominantly the consequence of adiposity, rather than the cause. We also include CpGs associated with elevated liver fat (19), CpGs whose methylation has been previously shown to differ in the adipose tissue of BMI-discordant MZ twin pairs (111), smoking-associated CpGs (112), and CpG sites that have been associated with weight loss (113). The number in between dollar signs links to the source from which each CpG was chosen, and is also included in the component diagrams.