相关数据集
A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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Additional file 8: of Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design
The small molecule/gene combinations constituting the reference chemical-genetic interactions used in this study. (XLSX 11 kb)
Figshare2016-12-15 更新60
Whole-genome CRISPR screen of etoposide-treated U2OS and U2OS p53KO cells, and RNAseq of U2OS cells incubated in media conditioned by etoposide-treated U2OS or U2OS p53KO cells.
CRISPR screen: U2OS or U2OS p53KO cells expressing Cas9 were transduced with a whole-genome library of CRISPR sgRNAs, then treated with either DMSO or etoposide. Differential sgRNA abundances were cal
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Additional file 21 of Identification of functional regulatory elements in the human genome using pooled CRISPR screens
Additional file 21: Table S16. Peak-level MAGeCK output (Peak Library/dCas9-KRAB/Doxorubicin)
Figshare2020-02-01 更新60
Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.
Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,
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