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Independent significant loci (P<5E-06) associated with GERD in multi-ancestry participants from COPDGene, ECLIPSE, and SPIROMICS.
Independent significant loci (P<5E-06) associated with GERD in multi-ancestry participants from COPDGene, ECLIPSE, and SPIROMICS.
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Figshare
2025-02-07 更新
2026-04-28 收录
胃食管反流病遗传学
多族裔基因变异
数据链接:
https://figshare.com/articles/dataset/Independent_significant_loci_P_5E-06_associated_with_GERD_in_multi-ancestry_participants_from_COPDGene_ECLIPSE_and_SPIROMICS_/28372145
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资源简介:
Independent significant loci (P
应用场景:
创建时间:
2025-02-07
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胃食管反流病遗传学
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Mega-analysis of genetic variants significantly associated (P<5E-06) with GERD in participants from TOPMed cohorts (COPDGene, ECLIPSE, SPIROMICS) with WGS data.
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GWASs were run in all participants without ancestry exclusion using GENESIS single variant association testing. Abbreviations: AA—African American; COPD—Chronic Obstructive Pulmonary Disease; LL—95% C
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Genetic correlation a between severity of GERD symptoms, inflammation components and metabolic syndrome components.
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The distribution of gastroesophageal reflux disease (GERD) in same-sexed dizygotic (DZ) and monozygotic (MZ) twin pairs.
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aOne twin has GERD, and the other not.
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