Additional file 1 of MDA5 variants trade antiviral activity for protection from autoimmune disease
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Additional file 1. Detailed fine mapping results for the five diseases analyzed. Each tab shows the fine mapping results for a single disease. The first column lists the chromosomal location and allele of the SNP. The second column shows the posterior inclusion probability (PIP) for the SNP, i.e. the probability this SNP is causal – these probabilities may sum more than 1 over SNPs if there are more than one credible sets. The remaining columns show the posterior probabilities (PP) that the SNP are in the ith credible set, with one column per credible set detected by SuSiE [36–38]. When there is only one credible set then the PIP equals the posterior probability for that credible set; when there is more than one credible set, the PIP is a summary measure over all sets.
提供机构:
Modis, Yorgo; Wallace, Chris; Singh, Rahul
创建时间:
2025-06-03



