Distribution of B16 melanoma tumour cells in mouse organs following different delivery routes.

aTumors in the endocardium 6/9; tumors in the myocardium 3/9.
bTumors in the endocardium 3/4; tumors in the myocardium 1/4.
cFore and hind limb muscles + diaphragm were examined in detail.
dFew isolated melanin-secreting B16-F0 cells were found associated with muscle surface of a single individual. No evidence of tumor invasion was observed.
iv: intra-venous 5×105 cells injected.
ip: intraperitoneal 1×103 cells injected.
TA: Tibialis anterior.