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Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

ChEBI2015-04-19 更新2026-07-21 收录

DNA损伤修复机制

单核苷酸修复图谱

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67941 数据链接链接失效反馈

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资源简介：

Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

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创建时间：

2015-04-19

CRISPRi筛选

DNA损伤修复机制

Data from the CRISPR library screen enabled us to isolate the target protein in this research. Using live-cell imaging, we were able to validate the involvement of the hits from the CRISPR library scr

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Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

酶-RNA复合物结构

DNA损伤修复机制

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

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Genome-wide maps of rH2A.X in wildtype and DNMT3b-KO HCT116 lines

DNA损伤修复机制

着丝粒稳定性分析

Dysfunction of DNA methyltransferase 3b (DNMT3b) causes centromere instability but the underlying mechanism is unclear. We found that enforced expression of RNase H1 that removes R-loops, nucleic stru

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Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice. Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice

DNA损伤修复机制

单核苷酸分辨率基因组学

In the present work we have applied analytical methods to map repair events in rDNA using data generated by the newly developed XR-seq genome-wide single nucleotide repair technology. We find that in

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DDR inhibition by E4orf4 is PP2A-dependent.

DNA损伤修复机制

磷酸化蛋白质相互作用

(A) L11 cells in which a PP2A-B55 shRNA can be transiently expressed following Dox induction were induced with Dox (+) or left untreated (-). 48 hrs later, the cells were transfected with an empty vec

Figshare2016-03-16 更新50

Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

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