To test the hypothesis that the disruption caused by TCDD in cardiomyocytes results from changes in DNA methylation and gene expression patterns, we established a stable mouse embryonic stem cell line

NIAID Data Ecosystem50

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

环境毒理表观遗传学

纳米材料生物效应

Humans are increasingly exposed to nanoparticles and, although many of their physiological effects have been described, the molecular mechanisms underlying them are still largely unknown. The present

Taylor & Francis Group2017-10-30 更新20

The interaction of DNMT1 and DNMT3A epigenetic enzymes with phthalates and perfluoroalkyl substances: an in silico approach

环境毒理表观遗传学

分子对接

The occurrence of long-lasting adverse effects of the environmental contaminants on human health is a current emerging issue. In particular, phthalates, poly- and perfluoroalkyl substances are propose

Taylor & Francis Group2023-01-31 更新50

Relative miRNA and mRNA expression involved in arsenic methylation

砷代谢分子调控

环境毒理表观遗传学

Three arsenic species in urine are measured using an atomic absorption spectrophotometer. RT-PCR is performed to detect the expression levels of AS3MT, 3 miRNAs, and 17 relative mRNAs in 43 workers pr

NIAID Data Ecosystem50

Zebrafish transgenerational methylation profiling in response to TCDD, 5-AZA and MeHg

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