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Cyclopentadiene-Phosphine/Palladium-Catalyzed Synthesis of Indolizines from Pyrrole and 1,4-Dibromo-1,3-butadienes

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Figshare2016-02-12 更新2026-04-29 收录
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The cyclopentadiene–phosphine ligand (L1) and palladium were found to be an efficient catalyst system to activate the α-C­(sp2)–H bond of pyrrole and indole derivatives. Various alkenyl or aryl dibromides could be used to react with pyrrole and indole derivatives to afford multisubstituted indolizines in high yields.

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2016-02-12
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