MicroRNA profiling of Wilms Tumour 1 deleted and induced embryonic stem cells

We report the microRNA profiles of the mouse embryonic stem cell (E14IV), which have been deleted for tumour suppressor Wilms' Tumour 1 (WT1), and induced with retinoic acid. Additionally, cells that had an inducibe WT1 expression where also used to compare the microRNA profile during different time points of WT1 induction. Examination of different microRNA profiles in wildtype embryonic stem cells were compared to Wt1 knockout ES cells, retionic acid treated ES cells and Wt1 KO ES cells, and i inducible induction of Wt1 at 12 hour and 24 hour timepoint.