ER, mitochondria and ISR regulation by mt-HSP70 and ATF5 upon procollagen misfolding (primary cells)
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https://www.ncbi.nlm.nih.gov/sra/SRP390662
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We used bulk RNA sequencing (bulk RNAseq) in primary osteoblast cultures to validate scRNASeq and srRNASeq findings on osteoblast cell stress response pathway to misfolding of type I procollagen with Gly610->Cys substitution in the triple helical region of alpha2(I) chain. Overall design: Primary parietal bone cells were isolated, cultured, and differentiated as described in Gorrell et al, Adv Sci, 2022
创建时间：
2022-08-23
