Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine

Protein Data Bank Japan2024-11-27 更新2026-03-21 收录

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Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-({[5-({[2-(3-fluorophenyl)ethyl]amino}methyl)pyridin-3-yl]oxy}methyl)-4-methylpyridin-2-amine, ACETATE ION, ... Authors: Li, H, Poulos, T.L. Deposit date: 2013-03-22 Release date: 2013-08-07 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.25 Å) Cite: In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures. Bioorg.Med.Chem., 21, 2013

牛源内皮型一氧化氮合酶（endothelial nitric oxide synthase）血红素结构域（heme domain）与6-(((5-(((3-氟苯乙基)氨基)甲基)吡啶-3-基)氧基)甲基)-4-甲基吡啶-2-胺形成复合物的结构。数据集组分：5,6,7,8-四氢生物蝶呤、6-({[5-({[2-(3-氟苯基)乙基]氨基}甲基)吡啶-3-基]氧基}甲基)-4-甲基吡啶-2-胺、乙酸根离子…… 作者：Li, H、Poulos, T.L. 提交日期：2013-03-22 发布日期：2013-08-07 最后修改日期：2024-11-27 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.25埃）引用文献：《寻找结构更简洁的强效选择性神经元型一氧化氮合酶抑制剂》，Bioorg.Med.Chem., 21, 2013

创建时间：

2013-03-22