Imaging (CEUS & MRI), clinical (neuroscores) and biological (mitochondria function) endpoints in a murine model of ischemic stroke (sham, pMCAO and tMCAO) treated with ciclosporin A (CsA)
收藏Figshare2025-03-27 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Imaging_CEUS_MRI_clinical_neuroscores_and_biological_mitochondria_function_endpoints_in_a_murine_model_of_ischemic_stroke_sham_pMCAO_and_tMCAO_treated_with_ciclosporin_A_CsA_/26064820/1
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资源简介：
The aims of this study were: (i) To evaluate mitochondrial dysfunctions (using CRC and OXPHOS analysis) in a murine model of MCAO (transient and permanent) using multimodal imaging (per-occlusion dynamic contrast-enhanced ultrasound (CEUS) assessment of the area-at-risk (AAR) and MRI at day 1 to evaluate infarct size) and neuroscore evaluation;(ii) To study CsA as a cytoprotective treatment potentially targeting mitochondria in the tMCAO model combining imaging approach, neuroscores assessment and mitochondrial function analyses (mPTP sensitivity to Ca2+ and OXPHOS).<br>
提供机构：
Wiart, Marlene
创建时间：
2025-03-27
