The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12f/l

The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12f/l Descriptor: 3-cyclohexyl-17-hydroxy-16,17-dimethoxy-12-methyl-15,18-dioxa-5-aza-1lambda5,17lambda5-diphosphapentacyclo[17.3.1.01,10.05,10.011,19]tricosa-10,19(23)-diene-4,11-quinone, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Buffa, V, Walz, C, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles. Angew.Chem.Int.Ed.Engl., 64, 2025