Associations of GWAS SNPs with Clinical Characteristics of Prostate Cancer.

†Aggressive prostate cancer was defined as having either a Gleason score 7 or higher, or at least two of the following characteristics documented on the pathology report: tumor invasiveness, tumor present at resection margins, prostate capsule invasion, seminal vesicle involvement, and lymph node involvement. Prostate cancer cases with missing information on disease pathological characteristics (n = 60) were excluded from these analyses.
*Odds ratios (ORs) and 95% CI for SNP genotypes for non-aggressive vs. aggressive prostate cancer were estimated using polytomous logistic regression models adjusted for age using allelic additive models; Bold font represent SNPs that show statistically significant associations at α = 0.002 (2-sided).
MAF = Minor Allele Frequency.