Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into dopaminergic (DAergic) neurons, which is one of the major cell types damaged in Parkinson’s disease (PD). For this r

NIAID Data Ecosystem70

Additional file 11 of Insights for disease modeling from single-cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture

单细胞转录组学

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Additional file 11: SuppTable4. Differential expression analysis between hiPSC-N and hiPSC-A.

DataCite Commons2024-08-18 更新50

A human pluripotent stem cell model of FSHD-affected skeletal muscles. Homo sapiens

肌营养不良模型

干细胞分化

Facioscapulohumeral muscular dystrophy (FSHD) represents a majorunmet clinical need arising from the progressive weakness and atrophy of skeletal muscles. The dearth of adequate experimental models ha

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Single_Cell_RNAseq_at_various_stages_of_HiPSCs_differentiating_toward_definitive_endoderm_and_endoderm_derived_lineages_

单细胞转录组学

干细胞分化

When comparing the differentiation capacities of pluripotent stem cell lines that have different genetic backgrounds, batch to batch experimental variablility poses a significant challenge, especially

NIAID Data Ecosystem50

Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population

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