Carbon dots and composite materials with excellent performances in cancer-targeted bioimaging and killing: a review - supplementary data

Carbon dots (CDs) are nanomaterials with excellent properties, including good biocompatibility, smallsize, ideal photoluminescence and surface modification, and are becoming one of the most attractivenanomaterials for the imaging, detection and treatment of tumors. Based on these advantages, CDscan be combined other materials to obtain composite particles with improved, even new, performance,mainly in photothermal and photodynamic therapies. This paper reviews the research progress of CDs andtheir composites in targeted tumor imaging, detection, diagnosis, drug delivery and tumor killing. It alsodiscusses and proposes the challenges and perspectives of their future applications in these fields. Thisreview provides ideas for future applications of novel CD-based materials in the diagnosis and treatmentof cancer.