Optical and Fluorescent Dual Sensing of Aminoalcohols by in Situ Generation of BODIPY-like Chromophore

A novel multifunctional
aminophenylboronic acid connected to a
diphenylketone gives both circular dichroism and fluorescence signals
by in situ generation of a BODIPY-like chromophore in the presence
of aminoalcohols. DFT calculations were used to understand the role
of each functional group in the mechanism. This new sensor can distinguish
different aminoalcohols and quantitatively indicate the concentration
of the substrate, allowing for the convenient determination of the
ee of racemic mixtures with a single probe.