Significant SNPs for candidate genes involved in downstream signaling pathways activated by CagA associated with gastric cancer in the discovery phase.

aTotal number of selected SNPs within each candidate gene.bMinor allele frequency among controls.cChromosome number.dRaw p-values calculated in the trend model with a cut-off level ≤0.01.e100,000 permutations for single SNP in the trend model.fAdjusted for age, smoking (never vs. ever), H. pylori infection (positive vs. negative) and CagA seropositivity (positive vs. negative).gSeven representative SNPs with a raw or permutated p valuehExcluded due to a SNP call rate *All BH-FDR p-values were not significant (p>0.05).