Gene expression analysis of human spinal motor neurons (MN) differentiated from ALS patient derived iPSC
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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP096788
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资源简介:
iPSC derived from a patient heterozygous for the SOD1 E100G mutation were genome edited to homozygous wild type using the CRISPR-Cas9 system. Both disease and isogenic corrected iPSC were differentiated into spinal motor neurons that were ISL1+ and CHAT+. Gene expression changes in MN were analyzed by RNA-sequencing.
创建时间:
2017-01-17



