The medium-chain free fatty acid receptor GPR84 is expressed in pro-inflammatory macrophages and mediates inflammatory sequelae in endometriosis. The medium-chain free fatty acid receptor GPR84 is expressed in pro-inflammatory macrophages and mediates inflammatory sequelae in endometriosis

RNA sequencing was used to investigate the transcriptomic response of primary human macrophages to stimulation of GPR84 and the effect of inhibition of this receptor with a range of antagonists. Overall design: RNA-seq of polyA-selected RNA from five healthy human donor macrophages exposed to a combination of agonists and antagonists for GPR84.