Visible-Light-Catalyzed [3 + 1 + 2] Coupling Annulations for the Synthesis of Unsymmetrical Trisubstituted Amino-1,3,5-triazines

A visible-light catalyzed [3 + 1 + 2] annulation for
the synthesis
of unsymmetrical trisubstituted amino-1,3,5-triazines from amidines,
isothiocyanates, and 1,1,3,3-tetramethylguanidines has been developed.
This method exhibits the advantages of easily available starting materials,
insensitive to air and moisture, wide substrate scopes, high step
economy, mild, metal- and ligand-free conditions, which has potential
applications in the organic, medicinal, and material chemistry.