Lipid loci with multiple signals in Europeans.

aLD (r2/D′) with SNP showing the strongest evidence of association at each locus.bβ: effect size from an additive model and corresponding to the effect allele, in the unit of mmol/L for HDL-C, LDL-C and natural log transformed TG.cP values of sequential conditional analyses, in which we added the SNP with the strongest evidence of association into the regression model as a covariate and tested for the next strongest SNP until the strongest SNP showed a conditional P value>10−4 and had no annotation suggesting potential function.dVariance explained by SNPs at each locus was estimated based on European samples.eP values of initial association in African Americans and East Asians.