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SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

ChEBI2012-07-18 更新2026-07-21 收录

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缺氧诱导因子降解

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33950 数据链接链接失效反馈

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SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

应用场景：

创建时间：

2012-07-18

癌症转移机制

细胞粘附

MYCT1, a target of c-Myc, inhibits laryngeal cancer cell migration, but the underlying mechanism remains unclear. In the study, we detected differentially expressed genes (DEGs) from laryngeal cancer

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NFIC1 suppresses migration and invasion of breast cancer cells through interferon-mediated Jak-STAT pathway

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Jak-STAT信号通路

NFIC1, the longest isoform of NFIC, is essential for the regulation on spatiotemporal expressions of drug-metabolizing genes in liver. However, the role of NFIC1 in breast cancer is not clear. Here we

NIAID Data Ecosystem40

NONO associates with PKM2 and directs histone H3 phosphorylation to promote tumor metastasis (CUT&Tag)

癌症转移机制

组蛋白修饰

Dysregulation of transcriptional programming and epigenome has been identified as fundamental driver of cancer. However, the molecular mechanisms in such processes remain poorly understood. Here, we r

NIAID Data Ecosystem30

Additional file 2 of An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes

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多组学整合分析

Additional file 2. Gene set characterization. Gene set characterization of the DE genes between early and late stages. The downregulated genes are significantly enriched for cancer-related gene signat

NIAID Data Ecosystem50

Flag-RBM47 HITS-CLIP in brain metastatic derivatives of MDA-MB-231

RNA结合蛋白靶标

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Brain metastatic breast cancer cells were subjected to HITS-CLIP to identify the targets of the RNA binding protein RBM47 MDA231-BrM2a is characterized in PMID: 19421193; Related data published toget

NIAID Data Ecosystem40

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

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