Integrin alpha4beta1 binds JAM2:JAM3
收藏reactome.org2025-01-16 收录
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Several key IgSF cell adhesion molecules engage integrin and in so doing impact on the multi-step paradigm of leukocyte emigration. The interaction between JAM2 (JAM-B) and Integrin alpha4beta1 (VLA-4) requires prior binding of JAM2 to JAM3 (JAM-C).
数种关键的 IgSF 细胞粘附分子与整合素相结合，从而影响白细胞迁移的多步骤范式。JAM2（JAM-B）与整合素 α4β1（VLA-4）之间的相互作用，需要 JAM2 先与 JAM3（JAM-C）结合。
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