five

Crystal structure of an inverse agonist antipsychotic drug pimavanserin-bound 5-HT2A

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Protein Data Bank Japan2024-10-09 更新2026-06-30 收录
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Crystal structure of an inverse agonist antipsychotic drug pimavanserin-bound 5-HT2A Descriptor: 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, Pimavanserin Authors: Oguma, T, Asada, H, Sekiguchi, Y, Imono, M, Iwata, S, Kusakabe, K. Deposit date: 2024-05-23 Release date: 2024-08-28 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Dual 5-HT 2A and 5-HT 2C Receptor Inverse Agonist That Affords In Vivo Antipsychotic Efficacy with Minimal hERG Inhibition for the Treatment of Dementia-Related Psychosis. J.Med.Chem., 67, 2024
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2024-05-23
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